Drug Discovery Targeting Metalloenzymes

An expertly curated collection of up-to-date resources covering metalloenzyme-targeting drug discovery Drug Discovery Targeting Metalloenzymes: Strategies and Applications (2 Volume Set) is an extensive collection of papers discussing the latest developments in the field of metalloenzyme-targeting drug discovery. The editor has curated some of the most cutting-edge explorations of metalloenzymes and the drug discovery applications animating discussion in the area today. The included resources examine informatics, tools, computational modeling advancements, high-throughput virtual screening techniques, and other practical, boundary-pushing topics. This curated compilation of resources explores the challenges associated with developing drugs that specifically target metalloenzymes, as well as the strategies professionals use to overcome them. It includes illustrative case studies that showcase successful drug discovery efforts, examinations of emerging trends in metalloenzyme-targeted therapies in the field of precision medicine, and experimental approaches to the study and discovery of drugs in this area. Inside the book: - Thorough introductions to metalloenzyme informatics and drug design- Comprehensive explorations of viral metalloenzyme-targeting drug discovery- Practical discussions of autotaxin targeting for therapeutic intervention- Complete treatments of substrate and inhibitor discovery of human glutaminyl cyclases Perfect for pharmaceutical chemists, biochemists, theoretical chemists, and medicinal chemists, the papers contained in the two volumes of Drug Discovery Targeting Metalloenzymes: Strategies and Applications will also benefit pharmaceutical engineers, biologists, and professionals in the pharmaceutical industry.